SCHEMBL3919950

SCHEMBL3919950

C[Si](C)(CCCCN)c1ccc([Si](C)(C)CCCCN)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.42
NR1H3 Q13133 3/20 0.42
HRH1 P35367 2/20 0.34
MAOA P21397 1/20 0.33
NFKB1 P19838 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA3 P07451 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
CA5A P35218 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
DNM1 Q05193 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486510 0.93 NR1H2 (0.43) NR1H2NR1H3HRH1MAOA
SCHEMBL3923573 0.82 NR1H2 (0.39) NR1H2NR1H3
SCHEMBL9723719 0.78
SCHEMBL7960568 0.78 NR1H2 (0.35) NR1H2NR1H3
SCHEMBL18717595 0.76 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL17124988 0.75 NR1H2 (0.63) NR1H2NR1H3
SCHEMBL18084487 0.75 MGAM (0.44) NR1H2NR1H3LMNATSHR
SCHEMBL25353827 0.73 NR1H2 (0.67) NR1H2NR1H3
SCHEMBL2007623 0.73 TAAR1 (0.41) NR1H2NR1H3
SCHEMBL2003777 0.73 TAAR1 (0.41) NR1H2NR1H3HRH1NFKB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8075824-B2 Polyimide film made of multicomponent polyimide and process of producing the same UBE INDUSTRIES, LTD. (JP) 2011-12-13 US disclosed
US-20090258211-A1 POLYIMIDE FILM MADE OF MULTICOMPONENT POLYIMIDE AND PROCESS OF PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2009-10-15 US disclosed