Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 3/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924470 | 0.96 | PLA2G1B (0.44) | PLA2G1BPLA2G2ASPHK1PSMD14MMP2 | |
| SCHEMBL3923171 | 0.85 | SPHK1 (0.42) | PLA2G1BPLA2G2ASPHK1PSMD14MMP2 | |
| SCHEMBL18315362 | 0.83 | PLA2G1B (0.52) | PLA2G1BPLA2G2ASPHK1GPR84FFAR1 | |
| SCHEMBL6455804 | 0.83 | PLA2G1B (0.52) | PLA2G1BPLA2G2ASPHK1GPR84FFAR1 | |
| SCHEMBL4189025 | 0.83 | PLA2G1B (0.52) | PLA2G1BPLA2G2ASPHK1GPR84FFAR1 | |
| SCHEMBL14356493 | 0.80 | SPHK1 (0.45) | PLA2G1BPLA2G2ASPHK1GPR84FFAR1 | |
| SCHEMBL2839149 | 0.78 | SPHK1 (0.44) | PLA2G1BPLA2G2ASPHK1GPR84FFAR1 | |
| SCHEMBL3922982 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL3924037 | 0.77 | SPHK1 (0.42) | PLA2G1BPLA2G2ASPHK1GPR84FFAR1 | |
| SCHEMBL6447998 | 0.76 | DNM1 (0.46) | PLA2G1BPLA2G2ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |