SCHEMBL392004

SCHEMBL392004

O=c1[nH]nccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11707071 0.98
SCHEMBL1456892 0.74 HCAR2 (0.41)
Hydrochloric Acid SCHEMBL29879478 0.72 KMT2A (0.46)
SCHEMBL11265687 0.71 NOTUM (0.59)
SCHEMBL28051817 0.71 NOTUM (0.62)
SCHEMBL390310 0.70
SCHEMBL1994489 0.70
SCHEMBL18797097 0.70
SCHEMBL8644938 0.70
SCHEMBL24880080 0.69 CYP19A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210198239-A1 COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR PLEXXIKON INC. 2021-07-01 US claimed
WO-2021113625-A1 COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR PLEXXIKON INC. (US) 2021-06-10 WO claimed
CN-108126656-A For the modified activated carbon absorbent of benzene in Adsorption wastewater from chemical industry 北京益清源环保科技有限公司 2018-06-08 CN claimed
WO-2026086928-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2026-04-30 WO disclosed
US-12612371-B2 Sigma-1 receptor ligands and therapeutic uses thereof UNIVERSITE DE STRASBOURG (FR) 2026-04-28 US disclosed
WO-2026047037-A1 MICROBIOCIDAL QUINOLINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-03-05 WO disclosed
EP-4703361-A1 PYRIDAZINONE TRPC4/5 INHIBITOR AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2026-03-04 EP disclosed
EP-4628167-A2 SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT Alkermes, Inc. (US) 2025-10-08 EP disclosed
EP-4065585-B1 SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT ALKERMES INC (US) 2025-08-20 EP disclosed
US-12378218-B2 Cyclopentane compounds DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-08-05 US disclosed
EP-4590396-A1 PCSK9 INHIBITORS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2025-07-30 EP disclosed
CN-1062636-A Be used for control (or) pyridazinone derivative and the composition of pre-pest control NISSAN CHEMICAL IND LTD (JP) 1992-07-15 CN disclosed
CN-1043129-A New piperazinyl alkyl-3 (2H)-pyridazinone, its preparation method and as the application of hypotensive agent CL PHARMA (AT) 1990-06-20 CN disclosed
US-4820819-A 5-phenyl-3[2H]-pyridazinone derivatives SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1989-04-11 US disclosed
CN-1030913-A Pyridazinone derivatives and compositions for controlling preventing pests NISSAN CHEMICAL IND LTD (JP) 1989-02-08 CN disclosed
EP-0283271-A2 Pyridazinone derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient UBE INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed
EP-0201417-B1 SURFACTANT COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE RHONE-POULENC CHIMIE (FR) 1988-09-14 EP disclosed
US-4678786-A Pharmaceutical compositions having β-adrenoceptor antagonist activity employing pyridazinone derivatives SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1987-07-07 US disclosed
EP-0138344-A2 Pyridazinones as beta-adrenoceptor antagonists SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1985-04-24 EP disclosed
US-4008086-A PYRIDONE OR PYRIDAZONE DERIVATIVES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-02-15 US disclosed