Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CPN1 | P15169 | 5/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344404 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL1199676 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL6544505 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL5363001 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TP53KDM4EGMNNLMNA | |
| Hydrochloric Acid SCHEMBL6544493 | 0.96 | ALDH1A1 (0.53) | ALDH1A1TP53KDM4EGMNNLMNA | |
| Hydrochloric Acid SCHEMBL5368323 | 0.96 | ALDH1A1 (0.53) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL4635154 | 0.96 | ALDH1A1 (0.52) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL5324531 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL16666936 | 0.85 | CPN1 (0.44) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL28968533 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TP53SMN1; SMN2EPHX1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024324-A1 | PROCESS FOR PREPARING GABAPENTIN | Pfizer Science and Technology Ireland Limited (IE) | 2009-02-18 | — | — | EP | claimed |
| WO-2007129286-A1 | PROCESS FOR PREPARING GABAPENTIN | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2007-11-15 | — | — | WO | claimed |
| EP-2024324-A1 | PROCESS FOR PREPARING GABAPENTIN | Pfizer Science and Technology Ireland Limited (IE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007129286-A1 | PROCESS FOR PREPARING GABAPENTIN | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2007-11-15 | — | — | WO | disclosed |