Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501304 | 0.95 | MAPK9 (0.36) | GRM5CNR1MAPK9MAPK10SQOR | |
| SCHEMBL501908 | 0.82 | SQOR (0.36) | GRM5CNR1MAPK9MAPK10SQOR | |
| SCHEMBL501211 | 0.81 | SQOR (0.35) | GRM5CNR1MAPK9MAPK10SQOR | |
| SCHEMBL10264980 | 0.78 | KDM4E (0.31) | HPGDALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL501586 | 0.78 | HPGD (0.48) | CNR1HPGDALDH1A1LMNATSHR | |
| SCHEMBL502073 | 0.77 | MAOB (0.40) | GRM5CNR1SQORMAOBHPGD | |
| SCHEMBL12752370 | 0.75 | SQOR (0.36) | GRM5CNR1MAPK9MAPK10SQOR | |
| SCHEMBL501518 | 0.74 | LRRK2 (0.37) | SQORMAOBHPGDALDH1A1LMNA | |
| SCHEMBL12752569 | 0.70 | MAOB (0.40) | GRM5SQORMAOBHPGDALDH1A1 | |
| SCHEMBL501449 | 0.69 | GAA (0.30) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005693-A1 | NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |