⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009418 | 0.72 | — | — | |
| SCHEMBL1766672 | 0.72 | — | — | |
| SCHEMBL8027623 | 0.72 | — | — | |
| SCHEMBL1767245 | 0.67 | LMNA (0.30) | — | |
| SCHEMBL3370827 | 0.67 | — | — | |
| SCHEMBL1767206 | 0.67 | — | — | |
| SCHEMBL6740966 | 0.67 | — | — | |
| SCHEMBL1766462 | 0.64 | — | — | |
| SCHEMBL26779 | 0.61 | — | — | |
| SCHEMBL3248008 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114864840-B | Preparation method of blue light perovskite light-emitting diode | 上海大学 | 2024-06-18 | — | — | CN | claimed |
| US-20220009900-A1 | N-TRIFLUORMETHYLCARBONYL COMPOUNDS AND METHODS FOR THEIR SYNTHESIS | RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2022-01-13 | — | — | US | claimed |
| EP-3883920-A1 | N-TRIFLUORMETHYLCARBONYL COMPOUNDS AND METHODS FOR THEIR SYNTHESIS | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen (DE) | 2021-09-29 | — | — | EP | claimed |
| CN-108218792-A | A kind of preparation method of trifluoromethyl substituted pyrimidines compound | 湖南华腾制药有限公司 | 2018-06-29 | — | — | CN | claimed |
| US-7148249-B2 | Indolinones substituted by heterocycles, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-12-12 | — | — | US | claimed |
| US-7115648-B2 | Indole-amide derivatives and their use as glycogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2006-10-03 | — | — | US | claimed |
| US-20050159472-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2005-07-21 | — | — | US | claimed |
| US-20050054710-A1 | Indolinones substituted by heterocycles, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-03-10 | — | — | US | claimed |
| EP-0377532-B1 | THIOFORMAMIDE DERIVATIVES | MAY AND BAKER LIMITED (GB) | 1992-07-29 | — | — | EP | claimed |
| EP-3957627-B1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SHIONOGI & CO (JP) | 2024-06-19 | — | — | EP | disclosed |
| CN-114864840-B | Preparation method of blue light perovskite light-emitting diode | 上海大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118146109-A | Method for synthesizing N-trifluoromethyl secondary amide compound from benzoyl isothiocyanate | 南京理工大学 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024096093-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2024-05-10 | — | — | WO | disclosed |
| CN-117945956-A | Synthesis method of N-trifluoromethyl sulfonamide compound | 南京理工大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-1997038988-A1 | HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |
| EP-0710880-A1 | Developing agent for silver halide photographic material, developing solution composition and method for developing silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |
| EP-0591030-A2 | 1-Heteroaryl-azetidines and -pyrrolidines as 5-HT3 agonists | SANOFI (FR) | 1994-04-06 | — | — | EP | disclosed |
| EP-0515265-A1 | Pyrimidin derivates, process for their preparation, the obtained intermediates, their use as medicines and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-11-25 | — | — | EP | disclosed |
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |