Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912115 | 1.00 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL7150042 | 0.86 | TSHR (0.36) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21964008 | 0.84 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL76123 | 0.84 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5458333 | 0.82 | TSHR (0.33) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL23923263 | 0.81 | TSHR (0.32) | TSHRCYP2C9PDE4AALDH1A1 | |
| SCHEMBL23923261 | 0.81 | TSHR (0.32) | TSHRCYP2C9PDE4AALDH1A1 | |
| SCHEMBL22688963 | 0.81 | TSHR (0.43) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL29455702 | 0.81 | TSHR (0.43) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL17866857 | 0.79 | TSHR (0.34) | TSHRCYP2C9PDE4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791967-B1 | METHODS AND COMPOSITIONS RELATING TO MANNURONIC ACID SPECIFIC BINDING PEPTIDES | BRIGHAM & WOMENS HOSPITAL (US) | 2013-11-27 | — | — | EP | disclosed |
| EP-1791967-A4 | METHODS AND COMPOSITIONS RELATING TO MANNURONIC ACID SPECIFIC BINDING PEPTIDES | BRIGHAM & WOMENS HOSPITAL (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1791967-A2 | METHODS AND COMPOSITIONS RELATING TO MANNURONIC ACID SPECIFIC BINDING PEPTIDES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006034395-A2 | METHODS AND COMPOSITIONS RELATING TO MANNURONIC ACID SPECIFIC BINDING PEPTIDES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060062779-A1 | Methods and compositions relating to mannuronic acid specific binding peptides | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-03-23 | — | — | US | disclosed |