Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455702 | 1.00 | TSHR (0.43) | TSHRCYP2C9PDE4ATP53SLC1A3 | |
| SCHEMBL570719 | 0.89 | TSHR (0.38) | TSHRCYP2C9PDE4ATP53SLC1A3 | |
| SCHEMBL10146952 | 0.88 | TSHR (0.41) | TSHRCYP2C9PDE4ATP53SLC1A3 | |
| SCHEMBL20986908 | 0.84 | SLC1A3 (0.45) | TSHRCYP2C9PDE4ATP53SLC1A3 | |
| SCHEMBL12610770 | 0.84 | SLC1A3 (0.45) | TSHRCYP2C9PDE4ATP53SLC1A3 | |
| SCHEMBL76123 | 0.81 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21964008 | 0.81 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20557370 | 0.81 | PDE4A (0.57) | TSHRCYP2C9PDE4AALDH1A1PGD | |
| SCHEMBL14621237 | 0.81 | PDE4A (0.57) | TSHRCYP2C9PDE4AALDH1A1PGD | |
| SCHEMBL21617331 | 0.81 | PDE4A (0.57) | TSHRCYP2C9PDE4APGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315957-A1 | ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-10-06 | — | — | US | claimed |
| US-20220315957-A1 | ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-10-06 | — | — | US | disclosed |
| EP-3969600-A1 | ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID | The Governing Council of the University of Toronto (CA) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020232536-A1 | ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-11-26 | — | — | WO | disclosed |