Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.73 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198608 | 0.86 | HTR6 (0.64) | HTR6DRD2HTR1AHTR2A | |
| SCHEMBL1537850 | 0.84 | HTR6 (1.00) | HTR6DRD2HTR1AHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL1537868 | 0.83 | HTR6 (0.98) | HTR6DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1537818 | 0.82 | HTR6 (0.75) | HTR6DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1537836 | 0.81 | HTR6 (0.74) | HTR6DRD2DRD3 | |
| SCHEMBL1537832 | 0.81 | HTR6 (0.80) | HTR6DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1537835 | 0.80 | HTR6 (0.79) | HTR6DRD2CYP2C9 | |
| Hydrochloric Acid SCHEMBL1537834 | 0.79 | HTR6 (0.77) | HTR6DRD2CYP2C9 | |
| SCHEMBL27513834 | 0.79 | HTR6 (0.83) | HTR6DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1537833 | 0.78 | HTR6 (0.76) | HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006267-A2 | N'-(2-HALOBENZYLIDENE)SULFONYLHYDRAZIDES AS INTERMEDIATES IN THE MANUFACTURE OF ARYLSULFONYLINDAZOLES | WYETH (US) | 2009-01-08 | — | — | WO | disclosed |