⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855576 | 0.90 | — | — | |
| SCHEMBL5855794 | 0.89 | RAB9A (0.32) | — | |
| SCHEMBL5984470 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5984802 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5984944 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5984979 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5986494 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5986160 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5984807 | 0.88 | RAB9A (0.36) | — | |
| SCHEMBL5985685 | 0.88 | RAB9A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005839-A2 | COMPOUNDS AND METHODS OF USE | THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) | 2009-01-08 | — | — | WO | claimed |
| US-9980928-B2 | Hydroxy aliphatic substituted phenyl aminoalkyl ether derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2018-05-29 | — | — | US | disclosed |
| US-20170239197-A1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2017-08-24 | — | — | US | disclosed |
| US-9707540-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-18 | — | — | US | disclosed |
| US-9624158-B2 | Hydroxy aliphatic substituted phenyl aminoalkyl ether derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2017-04-18 | — | — | US | disclosed |
| US-9611218-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2017-04-04 | — | — | US | disclosed |
| EP-2945702-B1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | PROUS INST FOR BIOMEDICAL RES S A (ES) | 2017-01-11 | — | — | EP | disclosed |
| US-20160271582-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-09-22 | — | — | US | disclosed |
| US-20160152568-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-06-02 | — | — | US | disclosed |
| EP-3022250-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD., AT THE WEI (IL) | 2016-05-25 | — | — | EP | disclosed |
| EP-0570594-B1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5604256-A | (7-(5-(1,3-DIOXANE-5YL)METHOXYIMINO-2-METHYL-8-(2-METHYLBUTYR -OXY)3-OXO-1,2,3,5,6,7,8,8A-OCTAHYDRO-1-NAPHTHYL)-3-HYDROXY-5 -OXOHEPTANOIC ACID AND SALTS | SANKYO COMPANY, LIMITED (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0570245-B1 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO CO (JP) | 1996-10-30 | — | — | EP | disclosed |
| US-5534654-A | ANTITUMOR, ANTIINFLAMMATORY, INHIBITOR OF LYMPHOCYTE ADHESIVE FACTORS | SHIONOGI & CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5403860-A | Octahydronaphthalene oxime compounds for cholesterol synthesis inhibition | SANKYO COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| EP-0570594-A1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0570245-A2 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0314435-B1 | OCTAHYDRONAPHTHALENE OXIME DERIVATIVES FOR CHOLESTEROL SYNTHESIS INHIBITION, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Sankyo Company Limited (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4997848-A | Enzyme inhibitors | SANKYO COMPANY, LIMITED (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0314435-A2 | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition, processes for their preparation and compositions containing them | Sankyo Company Limited (JP) | 1989-05-03 | — | — | EP | disclosed |