Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508129 | 0.91 | STING1 (0.53) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL16016991 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL24984253 | 0.89 | STING1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL30141106 | 0.89 | STING1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL4639562 | 0.88 | MEN1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL4639560 | 0.88 | MEN1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL4674780 | 0.88 | MEN1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL4639566 | 0.88 | MEN1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL4674783 | 0.88 | MEN1 (0.61) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 | |
| SCHEMBL20169881 | 0.88 | STING1 (0.50) | ALDH1A1CYP3A4MAPK1SMN1; SMN2STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067679-B2 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2006-06-27 | — | — | US | claimed |
| US-20050020512-A1 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INCORPORATED | 2005-01-27 | — | — | US | claimed |
| US-20040116718-A1 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2004-06-17 | — | — | US | claimed |
| US-7507831-B2 | Tetra- and penta-o-benzyl-protected, C-4 activated-epicatechin and -catechin monomers and processes for their preparation and use | MARS, INC. | 2009-03-24 | — | — | US | disclosed |
| US-20070276147-A1 | Synthesis of Oligomeric Epicatechin- and Catechin-Derived Procyanidins | KOZIKOWSKI ALAN P | 2007-11-29 | — | — | US | disclosed |
| US-7244855-B2 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INC. | 2007-07-17 | — | — | US | disclosed |
| US-20060173198-A1 | Synthesis of dimeric, trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | KOZIKOWSKI ALAN P | 2006-08-03 | — | — | US | disclosed |
| US-20050020512-A1 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INCORPORATED | 2005-01-27 | — | — | US | disclosed |
| US-20040116718-A1 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2004-06-17 | — | — | US | disclosed |