Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP12 | P39900 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640703 | 1.00 | MMP1 (0.53) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL3923157 | 1.00 | MMP1 (0.53) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL641215 | 0.89 | MMP1 (0.57) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL4006383 | 0.89 | MMP1 (0.57) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL641973 | 0.89 | MMP1 (0.59) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL641476 | 0.88 | MMP1 (0.63) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL639342 | 0.86 | MMP1 (0.53) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL640394 | 0.85 | MMP1 (0.48) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL641250 | 0.83 | MMP1 (0.56) | MMP1CYP2D6MMP9MMP12KCNH2 | |
| SCHEMBL3925576 | 0.82 | MMP1 (0.68) | MMP1CYP2D6MMP9MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009008920-A2 | HYDROXAMIC ACID DERIVATIVES OF 4-PHENYL 4-HYDROXY, 4-PHENYL 4-ALKOXY AND 4-PHENYL 4-ARYLALKOXY BUTYRIC ACID USEFUL AS THERAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING | PANTHERA BIOPHARMA, LLC. (US) | 2009-01-15 | — | — | WO | disclosed |