Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122065 | 0.98 | MAPT (0.45) | MAPTSMN1; SMN2ALOX15ELANESIRT2 | |
| SCHEMBL3925033 | 0.94 | TLR8 (0.40) | MAPTSMN1; SMN2ALOX15ELANESIRT2 | |
| SCHEMBL3922006 | 0.85 | TLR8 (0.37) | MAPTSMN1; SMN2ALOX15ALDH1A1TSHR | |
| SCHEMBL183395 | 0.75 | — | — | |
| SCHEMBL17895868 | 0.75 | CYP4F2 (0.48) | MAPTSMN1; SMN2ALOX15ELANEPTGS2 | |
| SCHEMBL11715954 | 0.74 | TTR (0.58) | MAPTALOX15ELANEALDH1A1 | |
| SCHEMBL11719258 | 0.73 | TTR (0.57) | ALOX15ELANEALDH1A1 | |
| SCHEMBL11717767 | 0.73 | TTR (0.57) | ALOX15ELANEALDH1A1 | |
| SCHEMBL19925250 | 0.71 | PPARA (0.55) | ALOX15ELANEALDH1A1TSHR | |
| SCHEMBL11717491 | 0.71 | KDM4E (0.48) | MAPTELANECYP3A4TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107548396-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| EP-2027101-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007131834-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007131834-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2007-11-22 | — | — | WO | disclosed |