Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPIF | P30405 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581595 | 0.85 | POLB (0.47) | MAPTPOLBNPC1RXFP1RAB9A | |
| SCHEMBL1447240 | 0.84 | POLB (0.46) | MAPTPOLBNPC1RXFP1RAB9A | |
| SCHEMBL9388459 | 0.71 | MEN1 (0.58) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL3590056 | 0.71 | EIF4E (0.44) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL1447215 | 0.71 | POLB (0.43) | MAPTGAAPOLBNPC1RXFP1 | |
| SCHEMBL1447848 | 0.68 | POLB (0.42) | MAPTPOLBNPC1RXFP1RAB9A | |
| SCHEMBL3581708 | 0.68 | TUBB4A (0.41) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL5865429 | 0.68 | MAPT (0.71) | CYP19A1CYP11B1CYP11B2MAPTGAA | |
| SCHEMBL3587958 | 0.68 | PPIA (0.41) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL8077523 | 0.67 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027091-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - Portela & Ca., S.A. (PT) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007117165-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & CA, S.A. (PT) | 2007-10-18 | — | — | WO | disclosed |