SCHEMBL3924286

SCHEMBL3924286

OC(CCl)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.53
LMNA P02545 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 3/20 0.42
MAPK1 P28482 2/20 0.42
HIF1A Q16665 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
GABBR2 O75899 1/20 0.41
GABBR1 Q9UBS5 1/20 0.41
GAA P10253 1/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
ADRB2 P07550 1/20 0.41
CYP2A6 P11509 1/20 0.40
IDO1 P14902 2/20 0.39
HSD17B10 Q99714 1/20 0.39
BRD4 O60885 1/20 0.39
HDAC4 P56524 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306502 1.00 AOC3 (0.53) AOC3LMNASMN1; SMN2TSHRMAPK1
SCHEMBL3924289 1.00 AOC3 (0.53) AOC3LMNASMN1; SMN2TSHRMAPK1
SCHEMBL29700206 0.82 AOC3 (0.55) AOC3LMNASMN1; SMN2TSHRMAPK1
SCHEMBL10799093 0.82 TAAR1 (0.39) AOC3LMNASMN1; SMN2TSHRHIF1A
SCHEMBL3917589 0.81 AOC3 (0.50) AOC3LMNASMN1; SMN2TSHRMAPK1
SCHEMBL3917591 0.81 AOC3 (0.50) AOC3LMNASMN1; SMN2TSHRMAPK1
SCHEMBL27504475 0.80 TAAR1 (0.60) LMNASMN1; SMN2TSHRHIF1ATDP1
SCHEMBL6715483 0.80 TAAR1 (0.60) LMNASMN1; SMN2TSHRHIF1ATDP1
SCHEMBL1155443 0.80 AOC3 (0.53) AOC3LMNASMN1; SMN2TSHRMAPK1
SCHEMBL4297797 0.80 AOC3 (0.53) AOC3LMNASMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718407-B1 Intermediates for the synthesis of eliprodil enantiomers and process for their preparation SANOFI SYNTHELABO (FR) 2002-02-13 EP claimed
US-5677168-A Enantiomeric separation of (RS)1-(4-chlorophenyl)-2-chloroethanol by lipase catalyzed hydrolysis of its acetate SYNTHELABO (FR) 1997-10-14 US claimed
EP-0718407-A1 Intermediates for the synthesis of eliprodil enantiomers and process for their preparation SYNTHELABO (FR) 1996-06-26 EP claimed
JP-8252097-A None JP disclosed
CN-119614529-A Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-03-14 CN disclosed
CN-110016444-B Acinetobacter ZJPH1806 and application thereof in preparation of miconazole chiral intermediate 浙江工业大学 2021-05-11 CN disclosed
CN-110016444-A Acinetobacter calcoaceticus ZJPH1806 and its application for preparing Miconazole chiral intermediate 浙江工业大学 2019-07-16 CN disclosed
WO-2017001733-A1 BICYCLIC HETEROCYCLE DERIVATIVES AS BROMODOMAIN INHIBITORS ORION CORPORATION (FI) 2017-01-05 WO disclosed
CN-101243040-B Synthesis method of mandipropamid and derivatives thereof SYNGENTA PARTICIPATIONS AG 2012-12-05 CN disclosed
US-7601667-B2 Ruthenium/iridium complexes; hydrogenation catalysts KANTO KAGAKU KABUSHIKI KAISHA (JP) 2009-10-13 US disclosed
EP-1934159-B1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF SE (DE) 2009-03-25 EP disclosed
US-5677168-A Enantiomeric separation of (RS)1-(4-chlorophenyl)-2-chloroethanol by lipase catalyzed hydrolysis of its acetate SYNTHELABO (FR) 1997-10-14 US disclosed
JP-H08252097-A INTERMEDIATE IN SYNTHESIS OF ENANTIOMER OF ELIPRODIL AND ITS PRODUCTION SYNTHELABO SA 1996-10-01 JP disclosed
EP-0718407-A1 Intermediates for the synthesis of eliprodil enantiomers and process for their preparation SYNTHELABO (FR) 1996-06-26 EP disclosed
EP-0718407-A1 Intermediates for the synthesis of eliprodil enantiomers and process for their preparation SYNTHELABO (FR) 1996-06-26 EP disclosed
US-5266485-A Biosynthesis KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-11-30 US disclosed
EP-0493617-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE (-)-2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL AND (-)-SUBSTITUTED STYRENE OXIDE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-07-08 EP disclosed
EP-0390777-A1 CYCLOCARBONATE COMPOUNDS DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-10-10 EP disclosed
WO-1989000565-A1 CYCLOCARBONATE COMPOUNDS DAINIPPON INK & CHEMICALS, INC. (JP) 1989-01-26 WO disclosed
US-4598085-A Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles JANSSEN PHARMACEUTICA N.V. (BE) 1986-07-01 US disclosed