Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5437078 | 1.00 | AOC3 (0.53) | AOC3PYGLTSHRMAPK1HIF1A | |
| SCHEMBL1155443 | 1.00 | AOC3 (0.53) | AOC3PYGLTSHRMAPK1HIF1A | |
| SCHEMBL5201275 | 0.88 | AOC3 (0.52) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL17438169 | 0.87 | TSHR (0.48) | AOC3TSHRHIF1ATDP1CYP3A4 | |
| SCHEMBL8115632 | 0.83 | AOC3 (0.52) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL8113426 | 0.83 | AOC3 (0.52) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL3185372 | 0.83 | AOC3 (0.52) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL27006320 | 0.82 | AOC3 (0.47) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL27130324 | 0.82 | AOC3 (0.47) | AOC3TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL29700206 | 0.82 | AOC3 (0.55) | AOC3TSHRMAPK1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250065315-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) | 2025-02-27 | — | — | US | disclosed |
| EP-4491270-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | The University of Hong Kong (HK) | 2025-01-15 | — | — | EP | disclosed |
| CN-119306769-A | Iron complexes for enantioselective cis dihydroxylation of olefins | 香港大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-119120634-A | Process for the preparation of (R) -oxiranes based on epoxide hydrolases | 杭州微远生物科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118147265-B | Chiral resolution method of oxirane compound based on epoxide hydrolase | 杭州微远生物科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118147265-A | Chiral resolution method of oxirane compound based on epoxide hydrolase | 杭州微远生物科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20230192633-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-06-22 | — | — | US | disclosed |
| CN-109294942-B | Kurthia gibsonii and application thereof in resolution of 1-phenyl-1, 2-glycol | 华南理工大学 | 2020-04-28 | — | — | CN | disclosed |
| US-20160097063-A1 | Production Of Enantiopure alpha-Hydroxy Carboxylic Acids From Alkenes By Cascade Biocatalysis | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-04-07 | — | — | US | disclosed |
| US-20160097063-A1 | Production Of Enantiopure alpha-Hydroxy Carboxylic Acids From Alkenes By Cascade Biocatalysis | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-04-07 | — | — | US | disclosed |
| US-20070281339-A1 | Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides | OXYRANE UK LIMITED (GB) | 2007-12-06 | — | — | US | disclosed |
| US-20050090669-A1 | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists | ASTELLAS PHARMA INC. (JP) | 2005-04-28 | — | — | US | disclosed |
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-0907635-B1 | HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL | SK CORP (KR) | 2002-09-25 | — | — | EP | disclosed |
| US-20010034365-A1 | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol | CHOI YONG MOON (US) | 2001-10-25 | — | — | US | disclosed |
| US-6127412-A | TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM, ESPECIALLY AS ANTICONVULSANTS, ANTIEPILEPTIC AND NEUROPROTECTIVE AGENTS AND CENTRALLY ACTING MUSCLE RELAXANTS | SK CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-6103759-A | COMPRISING PURE ENANTIOMERIC FORMS, AS WELL AS ENANTIOMERIC MIXTURES, OF (2-(2-CHLOROPHENYL)-2-HYDROXYETHYL)OXYCARBOXAMIDE; USEFUL FOR TRATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | SK CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0907635-A1 | HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL | SK Corporation (KR) | 1999-04-14 | — | — | EP | disclosed |
| US-5854283-A | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol | YUKONG LIMITED (KR) | 1998-12-29 | — | — | US | disclosed |
| WO-1997026241-A1 | HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL | SK CORPORATION (KR) | 1997-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192633-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | AOC3 3294/4885PYGL 663/4885TSHR 264/4885 |
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | AOC3 655/4885PYGL 4612/4885TSHR 3667/4885 |
| US-20010034365-A1 | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol | DDT, GRIK2, GABRD | AOC3 1009/4885PYGL 1797/4885TSHR 2528/4885 |
| US-20070281339-A1 | Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides | DERA, ERG28, EPHX2 | AOC3 550/4885PYGL 2945/4885TSHR 4867/4885 |
| US-20250065315-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | SQLE, NFE2L2, FECH | AOC3 170/4885PYGL 3837/4885TSHR 2082/4885 |
| US-20050090669-A1 | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | AOC3 375/4885PYGL 4585/4885TSHR 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.