SCHEMBL3924293

SCHEMBL3924293

Cc1ccccc1C(=O)N[SiH3]

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.55
POLB P06746 1/20 0.53
TYK2 P29597 1/20 0.53
MAPK1 P28482 1/20 0.53
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
GAA P10253 1/20 0.50
P2RX7 Q99572 1/20 0.49
DHODH Q02127 1/20 0.49
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140037 0.82 HPGD (0.64) HPGDSMN1; SMN2POLBTYK2NPC1
SCHEMBL2650229 0.82 POLB (0.72) HPGDSMN1; SMN2POLBTYK2NPC1
SCHEMBL29746319 0.80 HPGD (0.62) HPGDSMN1; SMN2POLBTYK2MAPK1
SCHEMBL311564 0.80 HPGD (0.62) HPGDSMN1; SMN2POLBTYK2MAPK1
SCHEMBL8773443 0.80 HPGD (0.62) HPGDSMN1; SMN2POLBTYK2MAPK1
SCHEMBL1276162 0.80 HPGD (0.62) HPGDSMN1; SMN2POLBTYK2MAPK1
SCHEMBL4815209 0.80 HPGD (0.62) HPGDSMN1; SMN2POLBTYK2MAPK1
SCHEMBL15129252 0.78 HPGD (0.60) HPGDSMN1; SMN2POLBTYK2NPC1
SCHEMBL1128274 0.78 HPGD (0.60) HPGDSMN1; SMN2POLBTYK2MAPK1
SCHEMBL4914462 0.78 HPGD (0.60) HPGDSMN1; SMN2POLBTYK2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015081148-A1 MOISTURE CURABLE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-04 WO claimed
CN-107109063-B Thermoplastic composition comprising polyamide and polysiloxane 汉高股份有限及两合公司 2021-02-19 CN disclosed
EP-2758487-A1 MULTI-STAGE METHODS AND COMPOSITIONS FOR DESENSITIZING SUBTERRANEAN FORMATIONS FACES Halliburton Energy Services, Inc. (US) 2014-07-30 EP disclosed
WO-2013043292-A1 MULTI-STAGE METHODS AND COMPOSITIONS FOR DESENSITIZING SUBTERRANEAN FORMATIONS FACES HALLIBURTON ENERGY SERVICES, INC. (US) 2013-03-28 WO disclosed
EP-2027229-A2 SILICONE-TACKIFIER MATRIXES AND METHODS OF USE THEREOF Halliburton Energy Services, Inc. (US) 2009-02-25 EP disclosed
WO-2007141519-A2 SILICONE-TACKIFIER MATRIXES AND METHODS OF USE THEREOF HALLIBURTON ENERGY SERVICES, INC. (US) 2007-12-13 WO disclosed
EP-0317765-A2 Monocomponent polysiloxane compositions curable by humidity BAYER AG (DE) 1989-05-31 EP disclosed