SCHEMBL8773443

SCHEMBL8773443

Cc1ccccc1C(=O)NO

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.62
SMN1; SMN2 Q16637 3/20 0.59
GAA P10253 3/20 0.59
KDM4E B2RXH2 2/20 0.59
MPO P05164 1/20 0.59
HIF1A Q16665 1/20 0.59
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
POLB P06746 1/20 0.55
TYK2 P29597 1/20 0.55
MMP3 P08254 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 1/20 0.52
MAPK1 P28482 2/20 0.51
TP53 P04637 1/20 0.51
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4815209 1.00 HPGD (0.62) HPGDSMN1; SMN2GAAKDM4EMPO
SCHEMBL3140037 0.84 HPGD (0.64) HPGDSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL2650229 0.84 POLB (0.72) HPGDSMN1; SMN2GAAKDM4ENPC1
SCHEMBL1331243 0.83 GAA (0.73) SMN1; SMN2GAAKDM4EMPOHIF1A
SCHEMBL6671895 0.83 NPC1 (0.51) HPGDSMN1; SMN2GAAKDM4EMPO
SCHEMBL29746319 0.82 HPGD (0.62) HPGDSMN1; SMN2GAANPC1RAB9A
SCHEMBL311564 0.82 HPGD (0.62) HPGDSMN1; SMN2GAANPC1RAB9A
SCHEMBL1276162 0.82 HPGD (0.62) HPGDSMN1; SMN2GAANPC1RAB9A
SCHEMBL9493594 0.81 ALDH1A1 (0.62) HPGDSMN1; SMN2GAAKDM4EMPO
SCHEMBL4914462 0.80 HPGD (0.60) HPGDSMN1; SMN2GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622964-A1 QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION Gilva Therapeutics Co., Ltd. (TW) 2025-10-01 EP claimed
US-20250297135-A1 CERIA AND HYDROXAMIC ACID CMP COMPOSITION ENTEGRIS, INC. 2025-09-25 US claimed
WO-2025085669-A1 QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION GILVA THERAPEUTICS CO., LTD. (CN) 2025-04-24 WO claimed
EP-3624804-B1 HISTONE DEACETYLASES (HDACS) INHIBITORS ANNJI PHARM CO LTD (TW) 2022-02-16 EP claimed
US-20250297135-A1 CERIA AND HYDROXAMIC ACID CMP COMPOSITION ENTEGRIS, INC. 2025-09-25 US disclosed
US-20250297134-A1 HIGH RATE BULK OXIDE CMP COMPOSITION ENTEGRIS, INC. 2025-09-25 US disclosed
EP-0647217-B1 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES ZENECA LTD (GB) 1997-10-29 EP disclosed