Bromide

Bromide

SCHEMBL3924302

Br.COC1=CC2=C([N+](=O)[O-])C=C1C2

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16701997 0.57 TDP1 (0.34) ALDH1A1TDP1
SCHEMBL16724660 0.53 TDP1 (0.34) ALDH1A1TDP1
SCHEMBL10771157 0.52 TDP1 (0.58) ALDH1A1TDP1
SCHEMBL29396391 0.51 TDP1 (0.62) ALDH1A1TDP1
SCHEMBL1179747 0.51 TDP1 (0.62) ALDH1A1TDP1
SCHEMBL10778338 0.50 ALDH1A1 (0.62) ALDH1A1TDP1
SCHEMBL29800558 0.50 ALDH1A1 (0.68) ALDH1A1TDP1
SCHEMBL210330 0.50 ALDH1A1 (0.68) ALDH1A1TDP1
SCHEMBL1502237 0.49 SMN1; SMN2 (0.54) ALDH1A1TDP1
Methoxymethane SCHEMBL27637909 0.49 HSD17B10 (0.67) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544736-B2 Methods of preparing latex particulates with reactive functional groups HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-06-09 US disclosed
EP-1502929-B1 Methods of preparing latex particulates with reactive functional groups HEWLETT PACKARD DEVELOPMENT CO (US) 2006-05-10 EP disclosed
US-20060047060-A1 Methods of preparing latex particulates with reactive functional groups ZHOU ZHANG-LIN 2006-03-02 US disclosed
US-6995206-B2 Methods of preparing latex particulates with reactive functional groups HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2006-02-07 US disclosed
US-20050027065-A1 Methods and preparing latex particulates with reactive functional groups HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. 2005-02-03 US disclosed
EP-1502929-A1 Methods of preparing latex particulates with reactive functional groups Hewlett-Packard Development Company, L.P. (US) 2005-02-02 EP disclosed