Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760252 | 0.98 | PLA2G1B (0.38) | SIGMAR1PLA2G1BPLA2G2APAOXHRH4 | |
| SCHEMBL3919959 | 0.95 | SIGMAR1 (0.38) | SIGMAR1PLA2G1BPLA2G2APAOXHRH4 | |
| SCHEMBL3921738 | 0.93 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2APAOXHRH3 | |
| SCHEMBL18207967 | 0.88 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2APAOXHRH3 | |
| SCHEMBL3922986 | 0.88 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2APAOXHRH3 | |
| SCHEMBL3929227 | 0.86 | SIGMAR1 (0.34) | SIGMAR1PLA2G1BPLA2G2APAOXALDH1A1 | |
| SCHEMBL973693 | 0.85 | KDM4E (0.35) | ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL11415551 | 0.85 | TSHR (0.40) | PLA2G1BPLA2G2AALDH1A1TSHRKDM4E | |
| SCHEMBL30799893 | 0.85 | KDM4E (0.35) | ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL20996696 | 0.84 | TDP1 (0.32) | PLA2G1BPLA2G2APAOXALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |