Dinitrochlorobenzene

Dinitrochlorobenzene

SCHEMBL39251

O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.69
TDP1 Q9NUW8 2/20 0.61
GPR35 Q9HC97 3/20 0.59
ALDH1A1 P00352 2/20 0.59
TSHR P16473 2/20 0.59
MAPK1 P28482 2/20 0.59
TP53 P04637 1/20 0.59
HPGD P15428 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HIF1A Q16665 1/20 0.59
VCAM1 P19320 9/20 0.58
TXNRD1 Q16881 1/20 0.57
TXNRD3 Q86VQ6 1/20 0.57
TXNRD2 Q9NNW7 1/20 0.57
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitrochlorobenzene SCHEMBL20472381 1.00 HSD17B10 (0.69) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL29349476 1.00 HSD17B10 (0.69) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL28203845 0.98 HSD17B10 (0.67) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL28156595 0.96 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL27749176 0.96 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL28145167 0.94 HSD17B10 (0.62) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL27914231 0.94 HSD17B10 (0.62) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL28826452 0.91 TDP1 (0.79) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL28791821 0.91 HSD17B10 (0.58) HSD17B10TDP1GPR35ALDH1A1TSHR
Dinitrochlorobenzene SCHEMBL28224203 0.91 VCAM1 (0.59) HSD17B10TDP1GPR35ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10468 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383529-B2 Pharmaceutical combination for the treatment of cancer Piramal Enterprises Limited (IN) 2025-08-12 US claimed
US-20250127746-A1 TOPICAL CONTACT SENSITIZERS TO TREAT CANCER SQUAREX PHARMACEUTICAL CORP (US) 2025-04-24 US claimed
CN-119746606-A Dinitrochlorobenzene production waste gas treatment device and technology 新绛县德鑫化工有限公司 2025-04-04 CN claimed
CN-119746741-A Dinitrochlorobenzene heat treatment production line 新绛县德鑫化工有限公司 2025-04-04 CN claimed
WO-2025059964-A1 METHOD FOR PREPARING ANTIGEN-DELIVERY PARTICLE 苏州尔生生物医药有限公司 2025-03-27 WO claimed
CN-119588265-A Dinitroproduct water washing and alkali washing liquid separation equipment and process 新绛县德鑫化工有限公司 2025-03-11 CN claimed
CN-119547760-A Method for establishing damp-heat type eczema animal model and application thereof 湖北中医药大学 2025-03-04 CN claimed
CN-113663674-B Preparation method and application of porous microspheres and reduction method of nitro compound 珠海派锐尔新材料有限公司 2025-02-14 CN claimed
CN-118987777-B Multilayer sand filter tank for dinitrochlorobenzene preparation and use method 山西恒锦盛科技有限公司 2024-12-31 CN claimed
CN-119075163-A Self-powered wearable diagnosis and treatment integrated patch for atopic dermatitis, preparation method and application 电子科技大学 2024-12-06 CN claimed
EP-0017513-A1 Electrophotographic member and process for forming a latent image RANK XEROX LIMITED (GB) 1980-10-15 EP claimed
US-4214592-A Patch for skin tests INSTITUT MERIEUX (FR) 1980-07-29 US claimed
EP-0012981-A1 Process for the preparation of 2,4-dinitrophenyl urea HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP claimed
EP-0011048-A1 A process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene Toms River Chemical Corporation (US) 1980-05-14 EP claimed
US-4175186-A CYCLIZATION OF A NITROHALOBENZENE COMPOUND WITH A DIALKYDITHIOCARBAMIC ACID THE ANSUL COMPANY (US) 1979-11-20 US claimed
US-4170708-A FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-10-09 US claimed
US-4129647-A Treatment of acne KLEIN EDMUND 1978-12-12 US claimed
US-4102927-A Process for the preparation of 2,4-dinitroaniline HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-25 US claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed
US-3993685-A Process for the production of urethanes ATLANTIC RICHFIELD COMPANY (US) 1976-11-23 US claimed