Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928618 | 0.84 | GNAI3 (0.58) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL25405485 | 0.81 | HDAC7 (0.56) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL5482980 | 0.80 | HDAC7 (0.43) | DPP7MMP2USP2MMP8 | |
| SCHEMBL6943898 | 0.79 | DPP7 (0.52) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL9462370 | 0.79 | DPP7 (0.52) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL12754572 | 0.79 | DPP7 (0.52) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL8374607 | 0.78 | EPHX1 (0.50) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL17167959 | 0.78 | DPP7 (0.76) | DPP7RRM1EPHX1GNAI3GNAO1 | |
| SCHEMBL23140154 | 0.78 | USP2 (0.61) | DPP7RRM1EPHX1MMP2USP2 | |
| SCHEMBL15764612 | 0.78 | DPP7 (0.76) | DPP7RRM1EPHX1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |