Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824702 | 0.78 | TSHR (0.43) | ALDH1A1TSHRIDO1AGXTKDM4E | |
| SCHEMBL12882981 | 0.78 | TSHR (0.43) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL3936959 | 0.76 | TSHR (0.44) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL21327698 | 0.75 | TSHR (0.48) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL28386404 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL13062713 | 0.75 | TSHR (0.45) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL502 | 0.75 | TSHR (0.52) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL8881644 | 0.75 | TSHR (0.52) | ALDH1A1TSHRIDO1AGXTCA1 | |
| SCHEMBL20357328 | 0.75 | TSHR (0.37) | ALDH1A1TSHRIDO1CA1CA2 | |
| SCHEMBL28211884 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRIDO1AGXTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |