Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 12/20 | 0.69 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.69 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.69 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.69 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.69 |
| ▸ | PSMB10 | P40306 | 10/20 | 0.69 |
| ▸ | PSMB11 | A5LHX3 | 9/20 | 0.69 |
| ▸ | PSMA7 | O14818 | 9/20 | 0.69 |
| ▸ | PSMB1 | P20618 | 9/20 | 0.69 |
| ▸ | PSMA1 | P25786 | 9/20 | 0.69 |
| ▸ | PSMA2 | P25787 | 9/20 | 0.69 |
| ▸ | PSMA3 | P25788 | 9/20 | 0.69 |
| ▸ | PSMA4 | P25789 | 9/20 | 0.69 |
| ▸ | PSMA5 | P28066 | 9/20 | 0.69 |
| ▸ | PSMB4 | P28070 | 9/20 | 0.69 |
| ▸ | PSMB3 | P49720 | 9/20 | 0.69 |
| ▸ | PSMB2 | P49721 | 9/20 | 0.69 |
| ▸ | PSMA6 | P60900 | 9/20 | 0.69 |
| ▸ | PSMA8 | Q8TAA3 | 9/20 | 0.69 |
| ▸ | PSMB7 | Q99436 | 9/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535687 | 0.99 | LONP1 (0.71) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL535688 | 0.99 | LONP1 (0.71) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL2127363 | 0.94 | LONP1 (0.76) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL2127299 | 0.89 | PSMB5 (0.69) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL2127921 | 0.89 | PSMB5 (0.69) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL680573 | 0.88 | LONP1 (0.68) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL8513905 | 0.88 | PSMB5 (0.58) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL1688075 | 0.88 | LONP1 (0.68) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL13078869 | 0.88 | CTSL (0.71) | LONP1PSMB5PSMB8PSMB9PSMB6 | |
| SCHEMBL2127762 | 0.88 | PSMB5 (0.73) | LONP1PSMB5PSMB8PSMB9PSMB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117741022-A | Method for detecting residual impurities in bortezomib intermediate | 深圳万乐药业有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117741022-A | Method for detecting residual impurities in bortezomib intermediate | 深圳万乐药业有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2009004350-A1 | METHODS FOR PREPARING BORTEZOMIB AND INTERMEDIATES USED IN ITS MANUFACTURE | PLIVA HRVATSKA D.O.O. (HR) | 2009-01-08 | — | — | WO | disclosed |