Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253178 | 0.98 | TBXAS1 (0.79) | TBXAS1NOS1 | |
| SCHEMBL27785977 | 0.98 | TBXAS1 (0.79) | TBXAS1NOS1 | |
| SCHEMBL27748530 | 0.98 | TBXAS1 (0.72) | TBXAS1TSHRKDM4ELMNANOS1 | |
| Hydrochloric Acid SCHEMBL25366753 | 0.98 | TBXAS1 (0.72) | TBXAS1TSHR | |
| SCHEMBL28252403 | 0.98 | TBXAS1 (0.79) | TBXAS1NOS1 | |
| SCHEMBL23803072 | 0.98 | TBXAS1 (0.79) | TBXAS1NOS1 | |
| SCHEMBL11568 | 0.93 | — | — | |
| Pyridine SCHEMBL27891847 | 0.91 | TBXAS1 (0.62) | TBXAS1TSHR | |
| SCHEMBL937596 | 0.89 | TBXAS1 (0.95) | TBXAS1 | |
| Acetic Acid SCHEMBL2488197 | 0.88 | TBXAS1 (0.61) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174938-A | 4-indole-2-aminopyrimidine compounds and application thereof | 浙江工业大学 | 2021-01-05 | — | — | CN | claimed |
| CN-109535158-B | Bisaryl maleimide compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-112174938-A | 4-indole-2-aminopyrimidine compounds and application thereof | 浙江工业大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-105037275-B | The method for preparing Zilpaterol and its salt | 英特威国际有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109535158-A | A kind of double arylmaleimides compounds and its pharmaceutically acceptable salt and its preparation method and application | 浙江工业大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-109254076-A | The preparation method of volatile organic acids gas sensor | 南京理工大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-105777751-B | Bisaryl maleimide compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 浙江工业大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105777751-A | Bisaryl maleimide compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 浙江工业大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-103130790-B | A kind of 3-benzoisoxazole-4-indolylmaleimides derivative and uses thereof | JIANG University OF TECHNOLOGY (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-104289093-A | Wet-process hydrogen sulfide waste gas purifying device and method | CHINA PETROLEUM & CHEMICAL | 2015-01-21 | — | — | CN | disclosed |
| US-6797823-B1 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-09-28 | — | — | US | disclosed |
| CN-1479738-A | thioether substituted imidazoquinoline compounds | 3M | 2004-03-03 | — | — | CN | disclosed |
| EP-1384712-A1 | Derivatives of N-((quinolinyl)oxy)-phenyl)-urea and N-((quinazolinyl)oxy)-phenyl)-urea with antitumor activity | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-1153920-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES | KIRIN BREWERY (JP) | 2003-10-29 | — | — | EP | disclosed |
| CN-1344254-A | Quinoline derivatives and quinazoline derivatives | KIRIN BREWERY (JP) | 2002-04-10 | — | — | CN | disclosed |
| EP-1153920-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES | KIRIN BEER KABUSHIKI KAISHA (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-4737495-A | ANTIALLERGENS, ANTISCHEMIC, HYPOTENSIVE AGENTS | DR. KARL TOMAE, GMBH (DE) | 1988-04-12 | — | — | US | disclosed |
| EP-0204349-A2 | Heteroaromatic amine derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-12-10 | — | — | EP | disclosed |
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |