SCHEMBL3928014

SCHEMBL3928014

[CH2]C#CCCCC[CH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5984884 0.97 RAB9A (0.31)
SCHEMBL5985780 0.97 RAB9A (0.31)
SCHEMBL5986289 0.97 RAB9A (0.31)
SCHEMBL5986074 0.97 RAB9A (0.31)
SCHEMBL5855746 0.97 RAB9A (0.31)
SCHEMBL5985126 0.97 RAB9A (0.31)
SCHEMBL5985239 0.97 RAB9A (0.31)
SCHEMBL5984438 0.97 RAB9A (0.31)
SCHEMBL5983964 0.97 RAB9A (0.31)
SCHEMBL5986154 0.97 RAB9A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009005839-A2 COMPOUNDS AND METHODS OF USE THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) 2009-01-08 WO claimed
US-9707540-B2 Metal-organic materials and method for preparation YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-07-18 US disclosed
US-9611218-B2 Metal-organic materials and method for preparation YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2017-04-04 US disclosed
US-20160271582-A1 METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2016-09-22 US disclosed
US-20160152568-A1 METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2016-06-02 US disclosed
EP-3022250-A1 METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION YEDA RESEARCH AND DEVELOPMENT CO. LTD., AT THE WEI (IL) 2016-05-25 EP disclosed
WO-2015008280-A1 METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION YEDA RESEARCH AND DEVELOPMENT CO. LTD AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) 2015-01-22 WO disclosed
WO-2009005839-A2 COMPOUNDS AND METHODS OF USE THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) 2009-01-08 WO disclosed
US-7226946-B2 Substituted phenol compounds useful for anesthesia and sedation THERAVANCE, INC. (US) 2007-06-05 US disclosed
US-7144906-B2 Heterocyclic compounds NIPPON SHINYAKU CO., LTD. (JP) 2006-12-05 US disclosed
EP-1304334-A1 NOVEL ANTIANDROGENIC AGENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-04-23 EP disclosed
WO-2003026632-A2 SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION THERAVANCE, INC. (US) 2003-04-03 WO disclosed
EP-1295875-A1 HETEROCYCLIC COMPOUNDS Nippon Shinyaku Co., Ltd. (JP) 2003-03-26 EP disclosed
EP-1219631-A1 ANTIANDROGEN AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-07-03 EP disclosed
EP-0570594-B1 HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE SHIONOGI & CO (JP) 1997-07-30 EP disclosed
US-5534654-A ANTITUMOR, ANTIINFLAMMATORY, INHIBITOR OF LYMPHOCYTE ADHESIVE FACTORS SHIONOGI & CO., LTD. (JP) 1996-07-09 US disclosed
EP-0570594-A1 HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE SHIONOGI & CO., LTD. (JP) 1993-11-24 EP disclosed
US-5039674-A Calcium antagonistics YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-08-13 US disclosed
US-4782160-A CALCIUM RECEPTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-11-01 US disclosed
EP-0276552-A1 1,4-dihydropyridine derivatives and their production YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-03 EP disclosed