Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928088 | 1.00 | DPP4 (0.43) | DPP4F2TAAR1HTR2ATSHR | |
| Hydrochloric Acid SCHEMBL7317204 | 0.97 | DPP4 (0.42) | DPP4F2TAAR1HTR2ATSHR | |
| SCHEMBL8522965 | 0.83 | DPP4 (0.45) | DPP4F2TAAR1HTR2ATSHR | |
| SCHEMBL9804521 | 0.80 | ACP3 (0.42) | HTR2AHRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6014583 | 0.75 | TRPA1 (0.44) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL6014580 | 0.75 | TRPA1 (0.44) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL8613849 | 0.74 | MEN1 (0.39) | DPP4F2TAAR1HTR2ATSHR | |
| SCHEMBL692130 | 0.74 | MEN1 (0.39) | DPP4F2TAAR1HTR2ATSHR | |
| SCHEMBL2387572 | 0.74 | DPP4 (0.38) | DPP4F2TAAR1HTR2ATSHR | |
| SCHEMBL2094186 | 0.74 | CYP2D6 (0.39) | DPP4F2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40851-E1 | 3,3-diphenylpropylamines, their use and preparation | PFIZER HEALTH AB (SE) | 2009-07-14 | — | — | US | claimed |
| US-RE39667-E1 | 3,3-Diphenylpropylamines, their use and preparation | PFIZER HEALTH AB (SE) | 2007-05-29 | — | — | US | claimed |
| EP-0667852-B1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-04-08 | — | — | EP | claimed |
| US-5559269-A | ANTICHOLINERGIC AGENTS | PHARMACIA AB (SE) | 1996-09-24 | — | — | US | claimed |
| EP-0667852-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-08-23 | — | — | EP | claimed |
| WO-1994011337-A9 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | — | 1995-07-06 | — | — | WO | claimed |
| WO-1994011337-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 1994-05-26 | — | — | WO | claimed |
| CN-105074514-A | Polarizing plate | SUMITOMO CHEMICAL CO | 2015-11-18 | — | — | CN | disclosed |
| US-RE40851-E1 | 3,3-diphenylpropylamines, their use and preparation | PFIZER HEALTH AB (SE) | 2009-07-14 | — | — | US | disclosed |
| US-RE39667-E1 | 3,3-Diphenylpropylamines, their use and preparation | PFIZER HEALTH AB (SE) | 2007-05-29 | — | — | US | disclosed |
| EP-1534239-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004054500-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20030096013-A1 | Preparation of submicron sized particles with polymorph control | BAXTER INTERNATIONAL INC. | 2003-05-22 | — | — | US | disclosed |
| EP-0667852-B1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-04-08 | — | — | EP | disclosed |
| US-5686464-A | ANTICHOLINERGIC AGENTS; URINARY INCONTINENCE TREATMENT | PHARMACIA AB (SE) | 1997-11-11 | — | — | US | disclosed |
| US-5559269-A | ANTICHOLINERGIC AGENTS | PHARMACIA AB (SE) | 1996-09-24 | — | — | US | disclosed |
| EP-0667852-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011337-A9 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | — | 1995-07-06 | — | — | WO | disclosed |
| WO-1994011337-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 1994-05-26 | — | — | WO | disclosed |