⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL5790939 | 0.88 | GDA (0.37) | — | |
| SCHEMBL14859078 | 0.75 | — | — | |
| SCHEMBL2785935 | 0.72 | KLK1 (0.36) | — | |
| SCHEMBL29574949 | 0.70 | — | — | |
| SCHEMBL14332224 | 0.70 | — | — | |
| SCHEMBL940899 | 0.70 | — | — | |
| SCHEMBL935566 | 0.70 | — | — | |
| SCHEMBL10414864 | 0.70 | — | — | |
| SCHEMBL935229 | 0.70 | — | — | |
| SCHEMBL935675 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209001-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p. A. (IT) | 2024-06-27 | — | — | US | claimed |
| WO-2024052512-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | WO | claimed |
| EP-4308122-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-01-24 | — | — | EP | claimed |
| EP-4308244-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-01-24 | — | — | EP | claimed |
| CN-117098765-A | Heterocyclic derivatives as Janus kinase inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116981459-A | Heterocyclic derivatives as janus kinase inhibitors | 奇斯药制品公司 | 2023-10-31 | — | — | CN | claimed |
| CN-111892601-B | Pyridopyrazolocinnoline compound and preparation method and application thereof | 陕西大美化工科技有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-111892601-A | Pyridopyrazolo cinnoline compound and preparation method and application thereof | 朱继强 | 2020-11-06 | — | — | CN | claimed |
| CN-111892597-A | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 朱继强 | 2020-11-06 | — | — | CN | claimed |
| EP-0820993-B1 | Process for the production of pyrazin-2-amines | LONZA AG (CH) | 2003-01-29 | — | — | EP | claimed |
| US-5998618-A | Process for preparing 3-alkoxy-5-alkypyrazin-2-amines | LONZA AG (CH) | 1999-12-07 | — | — | US | claimed |
| EP-0820993-A2 | Process for the production of 3-alkoxy-5-alkylpyrazin-2-amines | LONZA AG (CH) | 1998-01-28 | — | — | EP | claimed |
| EP-0262096-B1 | AMINOPYRAZINONES AND AMINOTRIAZINONES | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | claimed |
| US-4940482-A | SULFONYL UREA HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-07-10 | — | — | US | claimed |
| EP-0262096-A1 | Aminopyrazinones and aminotriazinones | CIBA-GEIGY AG (CH) | 1988-03-30 | — | — | EP | claimed |
| US-20260125364-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER (US) | 2026-05-07 | — | — | US | disclosed |
| CN-119968375-A | Heterocyclic derivatives as Janus kinase inhibitors | 奇斯药制品公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-0262096-A1 | Aminopyrazinones and aminotriazinones | CIBA-GEIGY AG (CH) | 1988-03-30 | — | — | EP | disclosed |
| EP-0262096-A1 | Aminopyrazinones and aminotriazinones | CIBA-GEIGY AG (CH) | 1988-03-30 | — | — | EP | disclosed |
| EP-0185346-A2 | Imidazo derivatives, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |