SCHEMBL3928403

SCHEMBL3928403

Cc1c(OCCN(C)C)c2cc(Br)ccc2n1S(=O)(=O)c1ccc(C(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 17/20 0.50
PTGDR Q13258 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3562247 0.92 HTR6 (0.47) HTR6PTGDRPTGDR2
SCHEMBL3556775 0.90 HTR6 (0.44) HTR6PTGDRPTGDR2
SCHEMBL3556124 0.90 HTR6 (0.45) HTR6PTGDRPTGDR2
SCHEMBL14953561 0.89 HTR6 (0.43) HTR6PTGDRPTGDR2
SCHEMBL3565226 0.88 HTR6 (0.56) HTR6
SCHEMBL3563498 0.88 HTR6 (0.48) HTR6PTGDRPTGDR2
SCHEMBL3926705 0.88 HTR6 (0.55) HTR6PTGDRPTGDR2
SCHEMBL3565768 0.86 HTR6 (0.47) HTR6
SCHEMBL3552018 0.86 HTR6 (0.48) HTR6PTGDRPTGDR2
SCHEMBL3561274 0.86 HTR6 (0.45) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567492-B1 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LTD (IN) 2013-05-22 EP claimed
US-7507835-B2 N-arylsulfonyl-3-aminoalkoxyindoles SUVEN LIFE SCIENCES LTD. (IN) 2009-03-24 US claimed