Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 9/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367749 | 0.90 | MEN1 (0.53) | MEN1KMT2ACCR5ADORA1 | |
| SCHEMBL3931440 | 0.90 | MEN1 (0.53) | MEN1KMT2ACCR5ADORA1 | |
| SCHEMBL3928637 | 0.88 | PTGDR2 (0.59) | CCR5PTGDR2 | |
| SCHEMBL3927273 | 0.85 | CCR5 (0.57) | CCR5PTGDR2 | |
| SCHEMBL3928972 | 0.85 | CCR5 (0.69) | CCR5 | |
| SCHEMBL3934113 | 0.84 | CCR5 (0.66) | MEN1KMT2ACCR5 | |
| SCHEMBL3933237 | 0.84 | CCR5 (0.56) | CCR5PTGDR2 | |
| SCHEMBL3936203 | 0.83 | CCR5 (0.57) | CCR5PTGDR2 | |
| SCHEMBL3927267 | 0.82 | PTGDR2 (0.56) | MEN1KMT2ACCR5PTGDR2 | |
| SCHEMBL3928880 | 0.82 | PTGDR2 (0.72) | MEN1KMT2ACCR5PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | claimed |
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |