Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.46 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.46 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067871 | 0.92 | CYP4F2 (0.54) | KCNQ3KCNQ2KCNQ4KCNQ5CYP4Z1 | |
| SCHEMBL25245034 | 0.92 | CYP4F2 (0.54) | KCNQ3KCNQ2KCNQ4KCNQ5CYP4Z1 | |
| SCHEMBL3587496 | 0.83 | KCNQ3 (0.50) | KCNQ3KCNQ2KCNQ4KCNQ5CYP4Z1 | |
| SCHEMBL2743461 | 0.81 | NPC1 (0.44) | KCNQ3KCNQ2KCNQ4KCNQ5SYK | |
| SCHEMBL30426996 | 0.80 | PLAAT3 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4MAPK1 | |
| SCHEMBL4853179 | 0.80 | PLAAT3 (0.47) | KCNQ3KCNQ2KCNQ4KCNQ5PLAAT3 | |
| SCHEMBL3938190 | 0.80 | PLAAT3 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4MAPK1 | |
| SCHEMBL21069038 | 0.78 | CYP4F2 (0.50) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| SCHEMBL29852322 | 0.78 | TDP1 (0.67) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| SCHEMBL13301958 | 0.78 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ4KCNQ5SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |