PLAAT3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL26657	0.45	9/20
SCHEMBL1027805	0.60	6/20
SCHEMBL710419	0.62	5/20
SCHEMBL1622156	0.50	5/20
SCHEMBL694045	0.58	4/20
SCHEMBL553140	0.50	4/20
SCHEMBL1920945	0.47	4/20
SCHEMBL442914	0.46	4/20
SCHEMBL440625	0.57	3/20
SCHEMBL1776	0.56	3/20
SCHEMBL991969	0.55	3/20
SCHEMBL1681600	0.54	3/20
SCHEMBL659686	0.54	3/20
SCHEMBL349314	0.53	3/20
SCHEMBL1154480	0.53	3/20
SCHEMBL1149507	0.52	3/20
SCHEMBL454778	0.51	3/20
SCHEMBL1990535	0.51	3/20
SCHEMBL1858472	0.51	3/20
SCHEMBL2005264	0.51	3/20

Clinical trials — most relevant to PLAAT3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Omega-3 Fatty Acids on the Human Gene Expression	PHASE4	COMPLETED
Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT	PHASE2	COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Assessment of Coronary Plaque Composition	PHASE1	COMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.	nan	UNKNOWN
Genetical Background of Non-alcoholic Fatty Liver Disease (NAFLD) in Diabetes Mellitus and in Chronic Kidney Disease	nan	UNKNOWN
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Choline to Improve Malnutrition and Enhance Cognition	nan	RECRUITING
Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity.	nan	COMPLETED
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children	nan	WITHDRAWN
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)	nan	UNKNOWN
Canola Oil Multicentre Intervention Trial	nan	COMPLETED
Human Liver ORganoids as a Model to Study the Development of Non-Alcoholic SteatOhepatitis (NASH)	nan	RECRUITING
Molecular Markers of Human Sperm Function	nan	WITHDRAWN
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing	nan	COMPLETED
Genetic Markers of CHD Risk in Men and Women	nan	COMPLETED
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study	nan	COMPLETED
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations	nan	COMPLETED
Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke	nan	COMPLETED
Duality of Lipids: the Athlete's Paradox	nan	COMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Genomic Dissection of a QTL Affecting the Lipid Profile	nan	WITHDRAWN
Gene Expression and Inflammation in Overweight Subjects	nan	COMPLETED
Omega-3 vs Very Low Calorie Diet for Liver Size Reduction	nan	UNKNOWN
Psychological and Biological Markers of Refractory Migraine	nan	UNKNOWN
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies	nan	UNKNOWN
Investigation of Copy Number Variations and Genetic Variants in POI	nan	RECRUITING
Phospholipid Hypothesis of Depression: From Molecular Biology, Neuroimaging to Behaviour	nan	COMPLETED
Gene Expression in Obesity and Insulin Resistance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PLAAT3 binder may also engage these)

Protein	Name	Similarity
Q5R611	—	1.000	Q5R611 →
Q8R3U1	—	1.000	Q8R3U1 →
P53817	—	0.991	P53817 →
PLAAT2	Phospholipase A and acyltransferase 2	0.990	landscape →
A0A0R4IY06	—	0.933	A0A0R4IY06 →
PLAAT4	Phospholipase A and acyltransferase 4	0.933	landscape →
Q9I8S4	—	0.929	Q9I8S4 →
Q9D020	—	0.922	Q9D020 →
Q8R127	—	0.920	Q8R127 →
D3ZLY0	—	0.920	D3ZLY0 →
P14019	—	0.919	P14019 →
P27119	—	0.918	P27119 →
Q6AY30	—	0.918	Q6AY30 →
P09057	—	0.917	P09057 →
Q9H0P0	—	0.917	Q9H0P0 →
Q04799	—	0.917	Q04799 →
P27118	—	0.915	P27118 →
O88451	—	0.915	O88451 →
P00860	—	0.915	P00860 →
Q3T067	—	0.914	Q3T067 →
P27117	—	0.913	P27117 →
O54909	—	0.913	O54909 →
P50170	—	0.913	P50170 →
Q1XAA8	—	0.912	Q1XAA8 →
Q8R2J9	—	0.912	Q8R2J9 →
E0CSI1	—	0.912	E0CSI1 →
Q8K4C0	—	0.912	Q8K4C0 →
P97872	—	0.911	P97872 →
Q6P4H8	—	0.911	Q6P4H8 →
Q9M8Z7	—	0.911	Q9M8Z7 →