Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30383446 | 0.82 | CTRB1 (0.64) | PTPN22CTRB1LDHAERN1CHEK1 | |
| SCHEMBL88069 | 0.82 | CTRB1 (0.64) | PTPN22CTRB1LDHAERN1CHEK1 | |
| Hydrochloric Acid SCHEMBL27766336 | 0.82 | CTRB1 (0.64) | PTPN22CTRB1LDHAERN1CHEK1 | |
| SCHEMBL1819743 | 0.81 | CTRB1 (0.62) | PTPN22CTRB1LDHAERN1CHEK1 | |
| SCHEMBL5145547 | 0.81 | CA1 (0.60) | PTPN22CTRB1LDHAERN1CA1 | |
| SCHEMBL7158072 | 0.81 | CTRB1 (0.62) | PTPN22CTRB1LDHAERN1CHEK1 | |
| Potassium SCHEMBL2292044 | 0.81 | CTRB1 (0.62) | PTPN22CTRB1LDHAERN1CHEK1 | |
| SCHEMBL7194110 | 0.81 | CTRB1 (0.62) | PTPN22CTRB1LDHAERN1CHEK1 | |
| Ammonia Solution, Strong SCHEMBL7758965 | 0.81 | CTRB1 (0.62) | PTPN22CTRB1LDHAERN1CHEK1 | |
| Ammonia Solution, Strong SCHEMBL27594855 | 0.81 | CTRB1 (0.62) | PTPN22CTRB1LDHAERN1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501981-B2 | CXCR2 inhibitors | SANOFI (FR) | 2013-08-06 | — | — | US | disclosed |
| US-20090227625-A1 | CXCR2 INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-10 | — | — | US | disclosed |
| CN-101478962-A | Novel CXCR2 inhibitors | SANOFI AVENTIS (FR) | 2009-07-08 | — | — | CN | disclosed |
| EP-2040688-A1 | NEW CXCR2 INHIBITORS | Sanofi-Aventis (FR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008000409-A1 | NEW CXCR2 INHIBITORS | SANOFI-AVENTIS (FR) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227625-A1 | CXCR2 INHIBITORS | CXCR2, CXCR1, CXCR4 | PTPN22 134/4885CTRB1 1047/4885LDHA 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.