SCHEMBL3928837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3927012	0.89	PDE4B (0.38)	GRM5CYP11B1CYP11B2CYP19A1CYP2C9
	SCHEMBL3931122	0.86	KMT2A (0.43)	CYP19A1SMPD1MEN1ALDH1A1GAA
	SCHEMBL3925115	0.85	KDM4E (0.40)	CYP11B1CYP11B2CYP19A1CYP2C9SMPD1
	SCHEMBL3925114	0.85	KDM4E (0.40)	CYP11B1CYP11B2CYP19A1CYP2C9SMPD1
	SCHEMBL3927709	0.84	MAOB (0.40)	GRM5SMPD1MEN1ALDH1A1GAA
	SCHEMBL3934029	0.81	DYRK1B (0.42)	GRM5DYRK1AMEN1ALDH1A1MAPT
	SCHEMBL3925118	0.81	BRD4 (0.32)	GRM5MEN1ALDH1A1GAAMAPT
	SCHEMBL3933515	0.78	LRRK2 (0.43)	CYP11B1CYP11B2SMPD1MEN1ALDH1A1
	SCHEMBL3929916	0.78	DYRK1B (0.40)	DYRK1AMEN1ALDH1A1MAPTKMT2A
	SCHEMBL3926276	0.78	VNN1 (0.37)	SMPD1MEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.