Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CBR1 | P16152 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397109 | 0.87 | TTR (0.50) | PTGS2LMNAMAPTNR1I2TTR | |
| SCHEMBL3929614 | 0.85 | EPAS1 (0.44) | PTGS2SLC6A2SLC6A3PTGS1EPAS1 | |
| SCHEMBL3930206 | 0.84 | PTGS2 (0.50) | PTGS2SCN9ALMNAMAPTPTGS1 | |
| SCHEMBL1331564 | 0.82 | PTGS2 (0.52) | PTGS2LMNAMAPTNR1I2TTR | |
| SCHEMBL5387735 | 0.80 | PTGS2 (0.47) | PTGS2LMNAMAPTNR1I2TTR | |
| SCHEMBL1332611 | 0.80 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1654842 | 0.79 | PTGDR2 (0.54) | SCN9ATTRMEN1KMT2APTGDR2 | |
| SCHEMBL3929611 | 0.75 | EPAS1 (0.45) | PTGS2HPGDSLC6A2SLC6A3PTGS1 | |
| SCHEMBL2395063 | 0.74 | PTGS2 (0.44) | PTGS2SLC6A2SLC6A3PTGS1EPAS1 | |
| SCHEMBL5397099 | 0.74 | PTGS2 (0.46) | PTGS2LMNAPTGS1EPAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007502806-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | claimed |
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |