Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332152 | 0.87 | PTGDR2 (0.55) | PTGDR2LRRK2 | |
| SCHEMBL585644 | 0.87 | PTGDR2 (0.67) | PTGDR2TSHRTDP1 | |
| SCHEMBL1332534 | 0.84 | PTGDR2 (0.70) | PTGDR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL5983987 | 0.83 | PTGDR2 (0.52) | PTGDR2PDK1PDK2PDK3PDK4 | |
| SCHEMBL1333288 | 0.78 | PTGDR2 (0.56) | PTGDR2TSHRTDP1 | |
| SCHEMBL1333486 | 0.78 | PTGDR2 (0.67) | PTGDR2TSHRTDP1 | |
| SCHEMBL585482 | 0.76 | PTGDR2 (0.52) | PTGDR2LRRK2 | |
| SCHEMBL1333312 | 0.76 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL1333182 | 0.73 | PTGDR2 (0.63) | PTGDR2TSHRTDP1 | |
| SCHEMBL1332553 | 0.72 | PTGDR2 (0.63) | PTGDR2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | claimed |