Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.63 |
| ▸ | CA1 | P00915 | 6/20 | 0.63 |
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534021 | 0.90 | CA12 (0.68) | CA2CA1CA12CA7CA14 | |
| SCHEMBL4411027 | 0.83 | CA12 (0.60) | CA2CA1CA12CA7CA14 | |
| SCHEMBL15161990 | 0.82 | CA2 (0.55) | CA2CA1CA12CA7CA14 | |
| Hydrochloric Acid SCHEMBL23855474 | 0.81 | CA2 (0.58) | CA2CA1CA12CA7CA14 | |
| SCHEMBL3648128 | 0.80 | CA2 (0.96) | CA2CA1CA12CA7CA14 | |
| SCHEMBL11690253 | 0.79 | CA12 (0.59) | CA2CA1CA12CA7CA14 | |
| SCHEMBL24990193 | 0.79 | CA2 (0.59) | CA2CA1CA12CA7CA14 | |
| SCHEMBL24990593 | 0.79 | CA12 (0.59) | CA2CA1CA12CA7CA14 | |
| SCHEMBL6029240 | 0.79 | CA12 (0.59) | CA2CA1CA12CA7CA14 | |
| SCHEMBL6029236 | 0.79 | CA12 (0.59) | CA2CA1CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121707-B1 | ANTIVIRAL INDOLES | ANGELETTI P IST RICHERCHE BIO (IT) | 2012-12-05 | — | — | EP | disclosed |
| US-8101595-B2 | Antiviral indoles | Istituto di Ricerche di Biologia Molecolare P. Angletti SpA (IT) | 2012-01-24 | — | — | US | disclosed |
| US-20100076046-A1 | Antiviral Indoles | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-03-25 | — | — | US | disclosed |
| EP-2121707-A1 | ANTIVIRAL INDOLES | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075103-A1 | ANTIVIRAL INDOLES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076046-A1 | Antiviral Indoles | IDO1, ZC3HAV1, IFNAR1 | CA2 4792/4885CA1 4555/4885CA12 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.