Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 17/20 | 0.48 |
| ▸ | KDM6B | O15054 | 8/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KDM4A | O75164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018318 | 0.83 | SIRT3 (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL30465694 | 0.82 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL3880004 | 0.82 | KDM4C (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL123203 | 0.82 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL7263236 | 0.81 | KDM4C (0.48) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL7509912 | 0.81 | KDM4C (0.48) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL2479238 | 0.81 | KDM4C (0.53) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL6207070 | 0.81 | KDM4C (0.48) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Acetic Acid SCHEMBL16666943 | 0.79 | KDM4C (0.49) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL9858541 | 0.79 | KDM4C (0.47) | KDM4CKDM6BKDM4DKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044050-A1 | NEW PYRIDINE ANALOGUES | Astra Zeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1904474-A1 | NEW PYRIDINE ANALOGUES | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2008004946-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |
| WO-2007008140-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |