Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275609 | 0.86 | SIRT3 (0.51) | SIRT3TDP1KDM4EHTTLOXL2 | |
| SCHEMBL3931892 | 0.83 | KDM4C (0.48) | SIRT3TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL9002466 | 0.83 | SIRT3 (0.61) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL3818201 | 0.81 | SIRT3 (0.55) | SIRT3TDP1KDM4EHTTLOXL2 | |
| SCHEMBL9018158 | 0.81 | SIRT3 (0.55) | SIRT3TDP1KDM4EHTTLOXL2 | |
| SCHEMBL9017967 | 0.81 | SIRT3 (0.50) | SIRT3TDP1KDM4EHTTLOXL2 | |
| SCHEMBL28769662 | 0.79 | SIRT3 (0.56) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL27372597 | 0.79 | SIRT3 (0.51) | SIRT3TDP1KDM4EHTTLOXL2 | |
| SCHEMBL9481707 | 0.77 | SIRT3 (0.50) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL1687197 | 0.76 | TDP1 (0.67) | SIRT3TDP1KDM4EHTTF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1044233-C | Amide compounds and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| CN-1081670-A | Amide compound and salt thereof, their manufacturing process and pesticide composition thereof | ISHIHARA SANGYO KAISHA (JP) | 1994-02-09 | — | — | CN | disclosed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | disclosed |