Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931906 | 0.86 | CRHR1 (0.58) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3920548 | 0.84 | CRHR1 (0.60) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3930547 | 0.82 | CRHR1 (0.54) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3931985 | 0.81 | CRHR1 (0.50) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3923164 | 0.81 | CRHR1 (0.57) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3923425 | 0.80 | CRHR1 (0.56) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3923248 | 0.79 | CRHR1 (0.56) | CRHR1CRHR2 | |
| SCHEMBL3931303 | 0.78 | CRHR1 (0.52) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3921150 | 0.78 | CRHR1 (0.52) | CRHR1CRHR2SMPD3 | |
| SCHEMBL3931377 | 0.77 | CRHR1 (0.52) | CRHR1CRHR2SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869049-B1 | IMIDAZOPYRIDAZINE COMPOUNDS | LILLY CO ELI (US) | 2009-03-04 | — | — | EP | disclosed |