Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2651099 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL10878421 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL201810 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL7591449 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL7006332 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL31438532 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL8875 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL6232190 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL14714623 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL1525005 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 40250 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079918-A | Isoxazole biphenyl compounds with CBP BRD and BRD4 BD2 inhibitory activity, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079137-A | Full diamond molecular pore canal graphite alkyne and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080003-A | Preparation method of spiro indolinone compound | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080414-A | Silicon carbide fiber precursor polycarbosilane and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076245-A | Microporous organic network hollow fiber membrane for efficient extraction of oka Tian Suangao and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079864-A | Dispiro naphthalene-1, 3' -indene-1 ',2' -pyrrolidone derivative, synthesis method and application | — | 2026-05-26 | — | — | CN | claimed |
| CN-119661858-B | Activatable semiconductor polymer and preparation method and application thereof | Jiageng Innovation Laboratory (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-117683044-B | Preparation method and application of asymmetric diaryl trithiophene/selenophene small molecular material | UNIVERSITY OF CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122059814-A | Preparation method of 1- (1, 1-dimethylpropoxy) -4-vinylbenzene | 西安爱德克美新材料有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122036738-A | Chiral indolone spirochroman compound, and synthetic method and application thereof | 成都大学 | 2026-05-15 | — | — | CN | claimed |
| EP-0199985-A2 | Benzoic-acid derivatives, pharmaceutical preparations comprising them and process for preparing these compounds and pharmaceutical preparations | Grünenthal GmbH (DE) | 1986-11-05 | — | — | EP | claimed |
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | claimed |
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | claimed |
| US-4223172-A | DEHYDROGENATION HALOGENATIVE WITH PALLADIUM-PHOSPHINE COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-09-16 | — | — | US | claimed |
| US-4210610-A | CHLOROARYLHYDROXY SUBSTITUTED ACETYLENES | GULF RESEARCH AND DEVELOPMENT COMPANY (US) | 1980-07-01 | — | — | US | claimed |
| US-4204078-A | REACTING NITROBROMOBENZENE WITH A HYDROXY-ACETYLENE COMPOUND; AMINE SOLVENT AND PALLADIUM COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-05-20 | — | — | US | claimed |
| EP-0001479-A2 | Process for the preparation of nitrophenylhydroxyacetylene and conversion to nitrophenylacetylene | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-04-18 | — | — | EP | claimed |
| US-4128588-A | PALLADIUM-PHOSPHINE COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-3991101-A | CARBONYLATION OF ALIPHATIC HALIDES USING NOBLE METAL COMPLEXES AS CATALYSTS | TEXACO INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-3937857-A | THERMAL DECOMPOSITION, NONCONDUCTIVE SUBSTRATE | AMP INCORPORATED (US) | 1976-02-10 | — | — | US | claimed |