Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932857 | 0.94 | FAAH (0.68) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3938179 | 0.93 | FAAH (0.71) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3939496 | 0.91 | FAAH (0.78) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3941324 | 0.89 | FAAH (0.73) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3935806 | 0.89 | FAAH (0.78) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3932306 | 0.88 | FAAH (0.71) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3934131 | 0.88 | FAAH (0.71) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3932773 | 0.87 | FAAH (0.70) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3929241 | 0.87 | FAAH (0.70) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL8132711 | 0.86 | FAAH (0.73) | FAAHALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |