Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510354 | 0.88 | MAOB (0.35) | MAOBSIRT1MCL1HIF1ASTING1 | |
| SCHEMBL5265504 | 0.84 | SIRT1 (0.33) | MAOBSIRT1MCL1HIF1AMAPT | |
| SCHEMBL14686069 | 0.80 | MAOB (0.36) | MAOBSIRT1MCL1HIF1AMAPT | |
| SCHEMBL5265282 | 0.79 | BCHE (0.31) | SIRT1HIF1AACHE | |
| SCHEMBL14686180 | 0.78 | STING1 (0.37) | MAOBSIRT1MCL1HIF1ASTING1 | |
| SCHEMBL5267902 | 0.76 | SIRT1 (0.33) | MAOBSIRT1MCL1HIF1AMAPT | |
| SCHEMBL6690567 | 0.74 | BCHE (0.38) | MAOBSIRT1MCL1HIF1AMAPT | |
| SCHEMBL5267639 | 0.72 | SIRT1 (0.35) | MAOBSIRT1MCL1MAPTL3MBTL1 | |
| SCHEMBL15442718 | 0.72 | BCHE (0.36) | MAOBSIRT1MCL1MAPTL3MBTL1 | |
| SCHEMBL3669027 | 0.72 | BCHE (0.36) | MAOBSIRT1MCL1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507831-B2 | Tetra- and penta-o-benzyl-protected, C-4 activated-epicatechin and -catechin monomers and processes for their preparation and use | MARS, INC. | 2009-03-24 | — | — | US | disclosed |
| US-20070276147-A1 | Synthesis of Oligomeric Epicatechin- and Catechin-Derived Procyanidins | KOZIKOWSKI ALAN P | 2007-11-29 | — | — | US | disclosed |
| US-7244855-B2 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INC. | 2007-07-17 | — | — | US | disclosed |
| US-20060173198-A1 | Synthesis of dimeric, trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | KOZIKOWSKI ALAN P | 2006-08-03 | — | — | US | disclosed |
| US-7067679-B2 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2006-06-27 | — | — | US | disclosed |
| US-20050020512-A1 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INCORPORATED | 2005-01-27 | — | — | US | disclosed |
| US-20040116718-A1 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2004-06-17 | — | — | US | disclosed |