Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.81 |
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.57 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138053 | 0.90 | PTPN11 (0.73) | PTPN11TLR2TLR1TLR6ESR1 | |
| SCHEMBL12171178 | 0.90 | PTPN11 (0.73) | PTPN11TLR2TLR1TLR6ESR1 | |
| SCHEMBL12171161 | 0.86 | PTPN11 (0.60) | PTPN11TLR2TLR1TLR6KDM4E | |
| SCHEMBL17589066 | 0.82 | PTPN11 (0.65) | PTPN11TLR2TLR1TLR6KDM4E | |
| SCHEMBL12610434 | 0.82 | PTPN11 (0.65) | PTPN11TLR2TLR1TLR6ESR1 | |
| SCHEMBL20207027 | 0.82 | TLR2 (0.60) | PTPN11TLR2TLR1TLR6ESR1 | |
| SCHEMBL20188864 | 0.82 | TLR2 (0.60) | PTPN11TLR2TLR1TLR6ESR1 | |
| Methyl 7-Deshydroxypyrogallin-4-Carboxylate SCHEMBL12609926 | 0.82 | PTPN11 (0.74) | PTPN11KDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL12610436 | 0.82 | PTPN11 (0.65) | PTPN11TLR2TLR1TLR6KDM4E | |
| SCHEMBL12610228 | 0.80 | PTPN11 (0.62) | PTPN11TLR2TLR1TLR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663442-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2017-05-30 | — | — | US | disclosed |
| US-9663442-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2017-05-30 | — | — | US | disclosed |
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-8784853-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8784853-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2014-07-22 | — | — | US | disclosed |
| EP-2584896-A2 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20130102463-A1 | Herbicidal Compositions | BASF SE (DE) | 2013-04-25 | — | — | US | disclosed |
| US-20120230925-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | BASF SE (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20120230925-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | BASF SE (DE) | 2012-09-13 | — | — | US | disclosed |
| WO-2011161105-A2 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011048011-A2 | BENZOTROPOLONE DERIVATIVES AS ANTIMICROBIAL AGENTS | BASF SE (DE) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120230925-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | CBR3, CBR1, CYP8B1 | PTPN11 4013/4885TLR2 2628/4885TLR1 1985/4885 |
| US-20130102463-A1 | Herbicidal Compositions | PPOX, PAOX, DDT | PTPN11 317/4885TLR2 4821/4885TLR1 4852/4885 |
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | CBR3, CBR1, CYP8B1 | PTPN11 3826/4885TLR2 2688/4885TLR1 2118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.