Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911299 | 0.84 | TSHR (0.46) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8074231 | 0.81 | TSHR (0.44) | TSHRCYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL15567587 | 0.81 | TSHR (0.44) | TSHRCYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL11791942 | 0.80 | EP300 (0.44) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11791621 | 0.80 | EP300 (0.44) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11791619 | 0.80 | EP300 (0.44) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11791945 | 0.80 | EP300 (0.44) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27859085 | 0.78 | TSHR (0.46) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10902357 | 0.75 | TSHR (0.69) | TSHRCYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL9238675 | 0.75 | TSHR (0.44) | TSHRCYP2C19ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544743-B2 | Process of controlled radical grafting of a polyolefin | UNIVERSITA' DI PISA (IT) | 2009-06-09 | — | — | US | disclosed |
| EP-1641838-B1 | A PROCESS OF CONTROLLED RADICAL GRAFTING OF A POLYOLEFIN | UNIV PISA (IT) | 2008-06-11 | — | — | EP | disclosed |
| US-20060148993-A1 | Process of controlled radical grafting of a polyolefin | UNIVERSITA' DI PISA (IT) | 2006-07-06 | — | — | US | disclosed |
| EP-1641838-A2 | A PROCESS OF CONTROLLED RADICAL GRAFTING OF A POLYOLEFIN | UNIVERSITA' DI PISA (IT) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004113399-A2 | A PROCESS OF CONTROLLED RADICAL GRAFTING OF A POLYOLEFIN | UNIVERSITA' DI PISA (IT) | 2004-12-29 | — | — | WO | disclosed |