SCHEMBL8074231

SCHEMBL8074231

CCC=C(Cc1ccco1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 6/20 0.42
ATM Q13315 1/20 0.41
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 2/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
GAA P10253 1/20 0.40
RIPK1 Q13546 1/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15567587 1.00 TSHR (0.44) TSHRCYP2C19ALDH1A1ATMGRIK1
SCHEMBL30911299 0.87 TSHR (0.46) TSHRCYP2C19ALDH1A1ATMKDM4E
SCHEMBL11791621 0.83 EP300 (0.44) TSHRCYP2C19ALDH1A1GRIK1KDM4E
SCHEMBL11791945 0.83 EP300 (0.44) TSHRCYP2C19ALDH1A1GRIK1KDM4E
SCHEMBL11791619 0.83 EP300 (0.44) TSHRCYP2C19ALDH1A1GRIK1KDM4E
SCHEMBL11791942 0.83 EP300 (0.44) TSHRCYP2C19ALDH1A1GRIK1KDM4E
SCHEMBL3933447 0.81 TSHR (0.45) TSHRCYP2C19ALDH1A1ATMKDM4E
SCHEMBL27859085 0.80 TSHR (0.46) TSHRCYP2C19ALDH1A1ATMKDM4E
SCHEMBL8074229 0.79 TSHR (0.45) TSHRCYP2C19ALDH1A1ATMKDM4E
SCHEMBL10902357 0.77 TSHR (0.69) TSHRCYP2C19ALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190023398-A1 Devices and Methods for Pest Control OLFACTOR LABORATORIES INC (US) 2019-01-24 US disclosed
WO-2017027836-A1 DEVICES AND METHODS FOR PEST CONTROL OLFACTOR LABORATORIES, INC. (US) 2017-02-16 WO disclosed
US-20150216182-A1 COMPOSITIONS AND METHODS OF THE ATTRACTION AND REPULSION OF INSECTS OLFACTOR LABORATORIES, INC. 2015-08-06 US disclosed
EP-2900062-A2 COMPOSITIONS AND METHODS FOR THE ATTRACTION AND REPULSION OF INSECTS OLFACTOR LABORATORIES, INC. (US) 2015-08-05 EP disclosed
WO-2014028835-A2 COMPOSITIONS AND METHODS FOR THE ATTRACTION AND REPULSION OF INSECTS OLFACTOR LABORATORIES INCORPORATED (US) 2014-02-20 WO disclosed
EP-0795596-B1 Fuel compositions SHELL INT RESEARCH (NL) 2000-10-11 EP disclosed
EP-0795596-A1 Fuel compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP disclosed