Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 19/20 | 0.89 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939066 | 0.94 | FAAH (0.82) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3936220 | 0.94 | FAAH (1.00) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3935343 | 0.92 | FAAH (0.89) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3935112 | 0.91 | FAAH (0.87) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3933423 | 0.91 | FAAH (0.87) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3941123 | 0.91 | FAAH (0.86) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3941489 | 0.89 | FAAH (0.83) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3941505 | 0.89 | FAAH (0.80) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3935920 | 0.89 | FAAH (0.86) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3931765 | 0.88 | FAAH (0.79) | FAAHMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |