Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935996 | 0.94 | HSD17B10 (0.63) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL13902144 | 0.90 | RORC (0.57) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3942313 | 0.89 | MAPT (0.54) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL4015128 | 0.85 | MAPT (0.51) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL13901891 | 0.83 | MAPT (0.56) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3941900 | 0.83 | MAPT (0.53) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3935954 | 0.83 | MAPT (0.56) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL4093749 | 0.83 | MAPT (0.56) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3933039 | 0.83 | MAP4K4 (0.61) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3933044 | 0.83 | MAP4K4 (0.61) | HSD17B10MAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | HSD17B10 1621/4885MAPT 3755/4885KDM4E 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.