SCHEMBL3933839 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	FAAH	O00519	11/20	0.86

▸	MAPT	P10636	2/20	0.43

▸	ALDH1A1	P00352	3/20	0.41

▸	LMNA	P02545	2/20	0.41

▸	HTT	P42858	2/20	0.41

▸	MAPK1	P28482	1/20	0.41

▸	MKNK1	Q9BUB5	2/20	0.40

▸	GBA1	P04062	1/20	0.39

▸	MEN1	O00255	2/20	0.38

▸	KMT2A	Q03164	2/20	0.38

▸	SMN1; SMN2	Q16637	1/20	0.38

▸	GPR6	P46095	1/20	0.37

▸	KDM4E	B2RXH2	1/20	0.37

▸	ALPL	P05186	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3941135	0.93	FAAH (1.00)	FAAHALDH1A1LMNAHTTMAPK1
SCHEMBL3942437	0.92	FAAH (0.88)	FAAHMAPTALDH1A1LMNAHTT
SCHEMBL3939389	0.91	FAAH (0.83)	FAAHMAPTALDH1A1LMNAHTT
SCHEMBL3933960	0.91	FAAH (0.86)	FAAHALDH1A1LMNAHTTMAPK1
SCHEMBL3941343	0.91	FAAH (0.86)	FAAHMAPTALDH1A1LMNAHTT
SCHEMBL3941586	0.91	FAAH (0.86)	FAAHALDH1A1LMNAHTTMAPK1
SCHEMBL3930701	0.91	FAAH (0.86)	FAAHALDH1A1LMNAHTTMAPK1
SCHEMBL3936263	0.91	FAAH (0.90)	FAAHALDH1A1LMNAHTTMAPK1
SCHEMBL3942978	0.91	FAAH (0.86)	FAAHALDH1A1LMNAHTTMAPK1
SCHEMBL4014147	0.90	FAAH (0.83)	FAAHALDH1A1LMNAHTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009011904-A1	COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF	RENOVIS, INC. (US)	2009-01-22	—	—	WO	disclosed