Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844609 | 0.83 | SPHK1 (0.45) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL9627370 | 0.81 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL27914015 | 0.81 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL10950621 | 0.81 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL9626907 | 0.81 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL8746175 | 0.79 | TSHR (0.47) | GPR84LMNAOPRM1 | |
| SCHEMBL6452480 | 0.79 | TSHR (0.47) | GPR84LMNAOPRM1 | |
| SCHEMBL125535 | 0.79 | TSHR (0.47) | GPR84LMNAOPRM1 | |
| SCHEMBL9166797 | 0.79 | TSHR (0.47) | GPR84LMNAOPRM1 | |
| SCHEMBL8824517 | 0.79 | TSHR (0.47) | GPR84LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |